Model Context Protocol for Agentic AI: Enabling Contextual Interoperability Across Systems
DOI:
https://doi.org/10.22399/ijcesen.3678Keywords:
Context, Agentic AI, Interoperability, MCPAbstract
The Model Context Protocol (MCP) is an open standard developed by Anthropic to facilitate seamless integration between large language models (LLMs) and external data sources or tools. By standardizing context exchange, MCP allows AI agents to interact with diverse systems in a secure and scalable manner. This paper explores MCP's architecture, components, and its role in enhancing agentic AI capabilities.The protocol introduces primitives such as tools, resources, prompts, and sampling to establish a structured interaction layer between models and environments. MCP’s modular design supports real-time, bidirectional communication over common transports like HTTP and WebSocket. Its adoption has enabled AI systems to become more flexible, interactive, and autonomous in enterprise and developer workflows. As context-aware intelligence becomes foundational, MCP offers a scalable pathway for building the next generation of agentic applications
References
[1] What Is Agentic AI?, (2025), IBM. https://www.ibm.com/think/topics/agentic-ai
[2] What is Agentic AI?, (2025). Salesforce US. https://www.salesforce.com/agentforce/what-is-agentic-ai/
[3] What is Agentic AI?, (2025). Key Trends in 2025 - Aisera, https://aisera.com/blog/agentic-ai/
[4] Agentic AI Vs AI Agents: 5 Differences and Why They Matter, (2025). Moveworks, https://www.moveworks.com/us/en/resources/blog/agentic-ai-vs-ai-agents-definitions-and-differences
[5] What is agentic AI? (2025). Red Hat, https://www.redhat.com/en/topics/ai/what-is-agentic-ai
[6] What Is Agentic AI?, (2025). NVIDIA Blog, https://blogs.nvidia.com/blog/what-is-agentic-ai/
[7] aisera.com, (2025), https://aisera.com/blog/agentic-ai/#:~:text=Agentic%20AI%20is%20an%20AI,(LLMs)%20and%20complex%20reasoning.
[8] Multi-Agent AI Systems, (2025). Aisera, https://aisera.com/blog/multi-agent-ai-system/
[9] Multi-Agent Collaboration Mechanisms: A Survey of LLMs, (2025) arXiv, https://arxiv.org/html/2501.06322v1
[10] What is Agentic AI?, (2025). UiPath, https://www.uipath.com/ai/agentic-ai
[11] What is Agentic AI?, (2025). An Easy Explanation for Everyone-YouTube, https://www.youtube.com/watch?v=-pqzyvRp3Tc
[12] From Experimentation to Deployment: Crafting an Agentic AI Strategy for Your Business, (2025). https://www.arionresearch.com/blog/h8qt2olb6jx4el4dirn0eakjmz6eob
[13] Agentic Workflows in Healthcare: Advancing Clinical Efficiency through AI Integration, (2025). https://www.researchgate.net/publication/389664995_Agentic_Workflows_in_Healthcare_Advancing_Clinical_Efficiency_through_AI_Integration
[14] How Model Context Protocol (MCP) Transforms Your AI into a Powerful Digital Assistant, (2025). Kanerika, https://kanerika.com/blogs/model-context-protocol-mcp/
[15] AI Spotlight: MCP (Model Context Protocol) and Agentic AI systems. Gravitee.io, (2025), https://www.gravitee.io/blog/mcp-model-context-protocol-agentic-ai
[16] Model Context Protocol (MCP) - A Deep Dive-WWT, (2025), https://www.wwt.com/blog/model-context-protocol-mcp-a-deep-dive
[17] How Model Context Protocol Connects LLMs to the Real World. (2025). Label Studio, https://labelstud.io/blog/how-model-context-protocol-connects-llms-to-the-real-world/
[18] Model Context Protocol: What You Need to Know, (2025). Gradient Flow. https://gradientflow.com/model-context-protocol-what-you-need-to-know/
[19] Introduction to Model Context Protocol (MCP)., (2025). LearnOpenCV. https://learnopencv.com/introduction-to-model-context-protocol/
[20] Introducing the Model Context Protocol- (2025). Anthropic. https://www.anthropic.com/news/model-context-protocol
[21] What is a MCP (Model Context Protocol) & How Does it Work?, (2025). Use Cases + Examples, https://www.shakudo.io/blog/mcp-model-context-protocol
[22] What is Model Context Protocol?, (2025). The emerging standard bridging AI and data, explained. https://www.zdnet.com/article/what-is-model-context-protocol-the-emerging-standard-bridging-ai-and-data-explained/
[23] aisera.com, (2025), https://aisera.com/blog/mcp-model-context-protocol/#:~:text=The%20Model%20Context%20Protocol%20(MCP)%2C%20launched%20by%20Anthropic%20in,tools%20via%20a%20unified%20interface.
[24] Model Context Protocol (MCP): The USB-C for AI?, (2025). Aisera. https://aisera.com/blog/mcp-model-context-protocol/
[25] Model Context Protocol (MCP), (2025). Anthropic API. https://docs.anthropic.com/en/docs/agents-and-tools/mcp
[26] A beginners Guide on Model Context Protocol (MCP), (2025). OpenCV. https://opencv.org/blog/model-context-protocol/
[27] Specification, (2025). Model Context Protocol. https://modelcontextprotocol.io/specification/2025-03-26
[28] A Survey of the Model Context Protocol (MCP): Standardizing Context to Enhance Large Language Models (LLMs), (2025). Preprints.org, https://www.preprints.org/manuscript/202504.0245/v1
[29] Is Anthropic's Model Context Protocol Right for You?, (2025). WillowTree Apps, https://www.willowtreeapps.com/craft/is-anthropic-model-context-protocol-right-for-you
[30] Model Context Protocol (MCP), (2025). Everything You Need to Know, https://zencoder.ai/blog/model-context-protocol
[31] Anthropic's Model Context Protocol (MCP) is way bigger than most people think, (2025). r/ClaudeAI. https://www.reddit.com/r/ClaudeAI/comments/1gzv8b9/anthropics_model_context_protocol_mcp_is_way/
[32] Moving from monolithic to microservices architecture for multi-agent systems. (2025). World Journal of Advanced Engineering Technology and Sciences, https://journalwjaets.com/sites/default/files/fulltext_pdf/WJAETS-2025-0480.pdf
[33] Agentic AI vs. Generative AI, (2025). IBM. https://www.ibm.com/think/topics/agentic-ai-vs-generative-ai
[34] How to Use Model Context Protocol the Right Way. (2025). Boomi, https://boomi.com/blog/model-context-protocol-how-to-use/
[35] MCP: The Breakthrough Protocol Powering the Next Era of Agentic AI, (2025). Fluid AI. https://www.fluid.ai/blog/mcp-the-breakthrough-protocol
[36] Model Context Protocol - The Foundation for Truly Agentic AI, (2025). Vinci Rufus. https://www.vincirufus.com/posts/mcp-foundation-for-agentic-ai/
[37] #14: What Is MCP, and Why Is Everyone – Suddenly!-Talking About It?, (2025). Hugging Face. https://huggingface.co/blog/Kseniase/mcp
[38] Model Context Protocol (MCP): The Key To Agentic AI, (2025). YouTube, https://www.youtube.com/watch?v=VChRPFUzJGA
[39] Frequently Asked Questions About Model Context Protocol (MCP) and Integrating with AI for Agentic Applications, (2025). Tenable. https://www.tenable.com/blog/faq-about-model-context-protocol-mcp-and-integrating-ai-for-agentic-applications
[40] MCP for Automation: Real-World Applications and Case Studies, (2025). Arsturn. https://www.arsturn.com/blog/mcp-for-automation-real-world-applications-and-case-studies
[41] Model Context Protocol (MCP) and Its Impact on AI-Driven Startups, (2025). https://www.aalpha.net/blog/model-context-protocol-mcp-and-its-impact-on-ai-driven-startups/
[42] Model Context Protocol (MCP) Explained, (2025). Humanloop. https://humanloop.com/blog/mcp
[43] Everything a Developer Needs to Know About the Model Context Protocol (MCP), (2025). Neo4j, https://neo4j.com/blog/developer/model-context-protocol/
[44] Advancing Multi-Agent Systems Through Model Context Protocol: Architecture, Implementation, and Applications, (2025). arXiv. https://arxiv.org/html/2504.21030v1
[45] Model Context Protocol (MCP): Landscape, Security Threats, and Future Research Directions, (2025). arXiv. https://arxiv.org/html/2503.23278
[46] Model Context Protocol (MCP): A Developer's Guide, (2025). Wallarm. https://www.wallarm.com/what/what-is-model-context-protocol-mcp
[47] Announcing the Agent2Agent Protocol (A2A), (2025). Google for Developers Blog. https://developers.googleblog.com/en/a2a-a-new-era-of-agent-interoperability/
[48] Papers by Prashant Kulkarni, (2025). AIModels.fyi. https://www.aimodels.fyi/author-profile/prashant-kulkarni-6369b855-996d-499d-908f-a4a23741e13e
[49] Multi-Agent Environment Tools: Top Frameworks, (2025). Rapid Innovation. https://www.rapidinnovation.io/post/frameworks-and-tools-for-building-multi-agent-environments
[50] Our abstract model for interoperating software agents identies three, (2025). ResearchGate. https://www.researchgate.net/figure/Our-abstract-model-for-interoperating-software-agents-identiies-three-classes-of_fig1_221613402
[51] An Introduction to MultiAgent Systems, (2025). Request PDF. ResearchGate. https://www.researchgate.net/publication/200027549_An_Introduction_to_MultiAgent_Systems
[52] Turbo prolog 2.0 basics, PDF, (2025). SlideShare. https://www.slideshare.net/slideshow/turbo-prolog-20-basics/139319370
[53] Google A2A Protocol: Language Support & Capabilities Explained, (2025). BytePlus. https://www.byteplus.com/en/topic/551575
[54] Building A Secure Agentic AI Application Leveraging Google's A2A Protocol, (2025). arXiv. https://arxiv.org/html/2504.16902
[55] Model Context Protocol Benefits: Key Advantages Explained, (2025). BytePlus. https://www.byteplus.com/en/topic/541182
[56] MCP Model Limitations: Key Challenges & Solutions, (2025). BytePlus. https://www.byteplus.com/en/topic/542231
[57] [2503.23278] Model Context Protocol (MCP): Landscape, Security Threats, and Future Research Directions, (2025). arXiv. https://arxiv.org/abs/2503.23278
[58] How MCP handles context management in high-throughput scenarios, (2025). Portkey. https://portkey.ai/blog/model-context-protocol-context-management-in-high-throughput/
[59] One AI Model Won't Fit All: Why Enterprise Workflows Need Multi-LLM and Contextual Interop, (2025). Fluid AI. https://www.fluid.ai/blog/why-enterprise-workflows-need-multi-llm-and-contextual-interop
[60] Interoperability Is Key to Unlocking Agentic AI's Future, (2025). Forrester. https://www.forrester.com/blogs/interoperability-is-key-to-unlocking-agentic-ais-future/
[61] Understanding Multi-Agent AI Frameworks, (2025). Ema. https://www.ema.co/additional-blogs/addition-blogs/understanding-multi-agent-ai-frameworks
[62] Agentic AI for Scientific Discovery, (2025). https://iclragenticai.github.io/
[63] MCP for Multimodal AI Applications: Benefits & Integration, (2025). BytePlus. https://www.byteplus.com/en/topic/541338
[64] RAG, AI Agents, and Agentic RAG: An In-Depth Review and Comparative Analysis, (2025). https://www.digitalocean.com/community/conceptual-articles/rag-ai-agents-agentic-rag-comparative-analysis
[65] Model Context Protocol Case Studies, (2025). Real-World Examples. BytePlus. https://www.byteplus.com/en/topic/541353
[66] Moving from monolithic to microservices architecture for multi-agent systems, (2025). https://journalwjaets.com/content/moving-monolithic-microservices-architecture-multi-agent-systems
[67] Agentic AI for Ontology Grounding over LLM-Discovered Scientific Schemas in a Human-in-the-Loop Workflow, (2025). Semantic Web Journal. https://www.semantic-web-journal.net/system/files/swj3871.pdf
[68] The Co-Leadership Challenge: What Healthcare Can Learn from the AI CEO Buzz, (2025). https://www.vktr.com/ai-technology/the-co-leadership-challenge-what-healthcare-can-learn-from-the-ai-ceo-buzz/
[69] Ahmadi, Arash & Sharifi, Safura & Banad, Yaser. (2025). MCP Bridge: A Lightweight, LLM-Agnostic RESTful Proxy for Model Context Protocol Servers. 10.48550/arXiv.2504.08999.
[70] Luo, Zhiling, Xiaorong Shi, Xuanrui Lin and Jinyang Gao, (2025). Evaluation Report on MCP Servers.
[71] LangChain, (2022). LangChain: Framework for developing applications powered by language models. https://github.com/langchain-ai/langchain .
[72] Jerry Liu, (2022). LlamaIndex: A data framework for LLM applications. https://github.com/run-llama/llama_index .
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